BioNetFit [electronic resource] : a fitting tool compatible with BioNetGen, NFsim and distributed computing environments

• Ngôn ngữ: eng
• Ký hiệu phân loại: 571.3 Anatomy and morphology
• Thông tin xuất bản: Washington, DC : Oak Ridge, Tenn. : United States. Department of Energy Work for Others Program ; Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy, 2015
• Mô tả vật lý: Size: p. 798-800 : , digital, PDF file.
• Bộ sưu tập: Metadata
• ID: 261067
• Chủ đề: 1. 59 basic biological sciences; 2. 60 applied life sciences; 3. Biological science

Tóm tắt

Rule-based models are analyzed with specialized simulators, such as those provided by the BioNetGen and NFsim open-source software packages. Here in this paper, we present BioNetFit, a general-purpose fitting tool that is compatible with BioNetGen and NFsim. BioNetFit is designed to take advantage of distributed computing resources. This feature facilitates fitting (i.e. optimization of parameter values for consistency with data) when simulations are computationally expensive.