Nanoscale materials for hyperthermal theranostics [electronic resource]

• Ngôn ngữ: eng
• Ký hiệu phân loại: 620.5 Nanotechnology
• Thông tin xuất bản: Richland, Wash. : Oak Ridge, Tenn. : Pacific Northwest National Laboratory (U.S.) ; Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy, 2015
• Mô tả vật lý: Size: p. 7115-7126 : , digital, PDF file.
• Bộ sưu tập: Metadata
• ID: 261180
• Chủ đề: 1. 60 applied life sciences; 2. 62 radiology and nuclear medicine; 3. 77 nanoscience and nanotechnology; 4. Angiogenesis; 5. Dna-repair; 6. Et al; 7. Magnetic resonance; 8. Nanoscale materials; 9. Optical fluorescence; 10. Radioemission; 11. Therapeutic approach

Tóm tắt

Recently, the use of nanoscale materials has attracted considerable attention with the aim of designing personalized therapeutic approaches that can enhance both spatial and temporal control over drug release, permeability, and uptake. Potential benefits to patients include the reduction of overall drug dosages, enabling the parallel delivery of different pharmaceuticals, and the possibility of enabling additional functionalities such as hyperthermia or deep-tissue imaging (LIF, PET, etc.) that complement and extend the efficacy of traditional chemotherapy and surgery. Our mini review is focused on an emerging class of nanometer-scale materials that can be used both to heat malignant tissue to reduce angiogenesis and DNA-repair while simultaneously offering complementary imaging capabilities based on radioemission, optical fluorescence, magnetic resonance, and photoacoustic methods.