Perylene-diimide-based nanoparticles as highly efficient photoacoustic agents for deep brain tumor imaging in living mice [electronic resource]

• Ngôn ngữ: eng
• Thông tin xuất bản: Washington, D.C. : Oak Ridge, Tenn. : United States. Dept. of Energy. Office of Science ; Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy, 2014
• Mô tả vật lý: Size: p. 843-847 : , digital, PDF file.
• Bộ sưu tập: Metadata
• ID: 261290
• Chủ đề: 1. 60 applied life sciences; 2. Brain tumor; 3. Deep tumor imaging; 4. Near-infrared-absorption; 5. Perylene-3,4,9,10-tetracarboxylic diimide nanoparticles; 6. Photoacoustic imaging

Tóm tắt

In order to promote preclinical and clinical applications of photoacoustic imaging, novel photoacoustic contrast agents are highly desired for molecular imaging of diseases, especially for deep tumor imaging. In this paper, perylene-3,4,9,10-tetracarboxylic diiimide-based near-infrared-absorptive organic nanoparticles are reported as an efficient agent for photoacoustic imaging of deep brain tumors in living mice with enhanced permeability and retention effect