HIV-1 Transmission during Early Infection in Men Who Have Sex with Men [electronic resource] : A Phylodynamic Analysis

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Tác giả:

Ngôn ngữ: eng

Ký hiệu phân loại: 576. Genetics and evolution

Thông tin xuất bản: Los Alamos, N.M. : Oak Ridge, Tenn. : Los Alamos National Laboratory ; Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy, 2013

Mô tả vật lý: Size: Article No. e1001568 : , digital, PDF file.

Bộ sưu tập: Metadata

ID: 261446

Conventional epidemiological surveillance of infectious diseases is focused on characterization of incident infections and estimation of the number of prevalent infections. Advances in methods for the analysis of the population-level genetic variation of viruses can potentially provide information about donors, not just recipients, of infection. Genetic sequences from many viruses are increasingly abundant, especially HIV, which is routinely sequenced for surveillance of drug resistance mutations. In this study, we conducted a phylodynamic analysis of HIV genetic sequence data and surveillance data from a US population of men who have sex with men (MSM) and estimated incidence and transmission rates by stage of infection.
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