Evaluation of the Lawrence Livermore Microbal Detection Array at the Statens Serum Institut [electronic resource]

• Ngôn ngữ: eng
• Ký hiệu phân loại: 616 Diseases
• Thông tin xuất bản: Washington, D.C. : Oak Ridge, Tenn. : United States. National Nuclear Security Administration ; Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy, 2021
• Mô tả vật lý: Size: 11 p. : , digital, PDF file.
• Bộ sưu tập: Metadata
• ID: 261714
• Chủ đề: 1. 59 basic biological sciences; 2. 60 applied life sciences; 3. 97 mathematics and computing; 4. Biological and medical sciences

Tóm tắt

This was a collaborative effort between Lawrence Livermore National Security, LLC as manager and operator of Lawrence Livermore National Laboratory (LLNL) and Statens Serum Institut to evaluate and transition the Lawrence Livermore Microarray Detection Array (LLMDA) analysis software package, the Composite Likelihood Maximization method (CLiMax) to the SSI. The SSI is a public enterprise under the Danish Ministry of Health that operates a microbiology reference laboratory for the Danish population and analyzes tens to thousands of human clinical samples annually. SSI has been collaborating with the LLNL team for several years to use the LLMDA to analyze viral and bacterial infections from human clinical samples. The collaboration has resulted in two joint publications thus far, describing improvements to LLMDA sample preparation, and the utility of the LLMDA for detecting emerging viruses in clinical samples.