Transforming Biological Science and Biomedical Practice [electronic resource]

• Ngôn ngữ: eng
• Ký hiệu phân loại: 571.3 Anatomy and morphology
• Thông tin xuất bản: Washington, D.C. : Oak Ridge, Tenn. : United States. Dept. of Energy. Office of Science ; Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy, 2018
• Mô tả vật lý: Size: 1 p. : , digital, PDF file.
• Bộ sưu tập: Metadata
• ID: 261902
• Chủ đề: 1. 59 basic biological sciences; 2. 60 applied life sciences

Tóm tắt

Opioid overdoses killed more than 50,000 people in the U.S. in 2016, reaching epidemic proportions. New opioid drugs that suppress pain but are neither addictive nor likely to cause overdose deaths are now in the pharmaceutical pipeline, the result of decades of research into how medicines attach to and communicate with the body?s cells. Critical to that research was a new method of determining the structure of large biological molecules, using extremely powerful beams of X-rays developed and supported at shared research facilities by the Basic Energy Sciences (BES) office of DOE. Such X-ray studies are now central to new drug development: the BES facilities are used by the pharmaceutical industry to screen most new drug candidates.