APPLICATIONS OF BIOTECHNOLOGY IN DEVELOPMENT OF BIOMATERIALS [electronic resource] : NANOTECHNOLOGY AND BIOFILMS

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Tác giả:

Ngôn ngữ: eng

Ký hiệu phân loại: 660.6 Biotechnology

Thông tin xuất bản: Aiken, S.C. : Oak Ridge, Tenn. : United States. Dept. of Energy. Savannah River Site ; Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy, 2010

Mô tả vật lý: Medium: ED : , digital, PDF file.

Bộ sưu tập: Metadata

ID: 262385

Biotechnology is the application of biological techniques to develop new tools and products for medicine and industry. Due to various properties including chemical stability, biocompatibility, and specific activity, e.g. antimicrobial properties, many new and novel materials are being investigated for use in biosensing, drug delivery, hemodialysis, and other medical applications. Many of these materials are less than 100 nanometers in size. Nanotechnology is the engineering discipline encompassing designing, producing, testing, and using structures and devices less than 100 nanometers. One of the challenges associated with biomaterials is microbial contamination that can lead to infections. In recent work we have examined the functionalization of nanoporous biomaterials and antimicrobial activities of nanocrystalline diamond materials. In vitro testing has revealed little antimicrobial activity against Pseudomonas fluorescens bacteria and associated biofilm formation that enhances recalcitrance to antimicrobial agents including disinfectants and antibiotics. Laser scanning confocal microscopy studies further demonstrated properties and characteristics of the material with regard to biofilm formation.
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