Deciphering mixotrophic <em>Clostridium formicoaceticum</em> metabolism and energy conservation [electronic resource] : Genomic analysis and experimental studies

 0 Người đánh giá. Xếp hạng trung bình 0

Tác giả:

Ngôn ngữ: eng

Ký hiệu phân loại: 621.48 Nuclear engineering

Thông tin xuất bản: Washington, D.C. : Oak Ridge, Tenn. : United States. Dept. of Energy. Office of Energy Efficiency and Renewable Energy ; Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy, 2018

Mô tả vật lý: Size: p. 1687-1694 : , digital, PDF file.

Bộ sưu tập: Metadata

ID: 262891

 <
 em>
 Clostridium<
 /em>
  formicoaceticum, a Gram-negative mixotrophic homoacetogen, produces acetic acid as the sole metabolic product from various carbon sources, including fructose, glycerol, formate, and CO<
 sub>
 2<
 /sub>
 . Its genome of 4.59-Mbp contains a highly conserved Wood-Ljungdahl pathway gene cluster with the same layout as that in other mixotrophic acetogens, including <
 em>
 Clostridium aceticum<
 /em>
 , <
 em>
 Clostridium carboxidivorans<
 /em>
 , and <
 em>
 Clostridium ljungdahlii<
 /em>
 . For energy conservation, <
 em>
 C. formicoaceticum<
 /em>
  does not have all the genes required for the synthesis of cytochrome or quinone used for generating proton gradient in H<
 sup>
 +<
 /sup>
 -dependent acetogens such as <
 em>
 Moorella thermoacetica<
 /em>

  instead, it has the Rnf system and a Na<
 sup>
 +<
 /sup>
 -translocating ATPase similar to the one in <
 em>
 Acetobacterium<
 /em>
  woodii. Furthermore its growth in both heterotrophic and autotrophic media were dependent on the sodium concentration. <
 em>
 C. formicoaceticum<
 /em>
  has genes encoding acetaldehyde dehydrogenases, alcohol dehydrogenases, and aldehyde oxidoreductases, which could convert acetyl-CoA and acetate to ethanol and butyrate to butanol under excessive reducing equivalent conditions.
Tạo bộ sưu tập với mã QR

THƯ VIỆN - TRƯỜNG ĐẠI HỌC CÔNG NGHỆ TP.HCM

ĐT: (028) 71010608 | Email: tt.thuvien@hutech.edu.vn

Copyright @2024 THƯ VIỆN HUTECH