In this assessment, we have evaluated target minimum biomass selling prices (MBSPs) of algae biomass production for four photobioreactor (PBR) designs compared to a previous open pond target case. We utilized techno-economic assessment modeling to determine if the target PBR cases can compete with open ponds for low-cost commodity fuels in an 'n<
sup>
th<
/sup>
-plant' scenario. In the process, algal biomass is produced in one of the five cultivation options, including: open ponds, horizontal tubes, helical tubes, and two vertical bag/panel designs termed 'GWP-II flat panels' and 'Leidos hanging bags.' The projected target cultivation productivity for each PBR design was estimated based on the most credible literature data presenting PBR and pond cultivation on a directly comparable basis, and then extrapolating out to the future. Resulting productivities on an aerial basis were estimated to range from 25 g/m<
sup>
2<
/sup>
/day to 52.5 g/m<
sup>
2<
/sup>
/day (cultivation area). CO<
sub>
2<
/sub>
, nutrients, and algae inoculum are supplied to the production area. After cultivation, the biomass is dewatered to 20 wt% solids in three stages including in-ground gravity settling, membrane filtration, and centrifugation. CO<
sub>
2<
/sub>
piping, water piping, and storage are also included in the analysis. Based on our recently published 'algae farm' design report, the open pond cultivation benchmark was set at an MBSP of $494/ton ash-free dry weight (AFDW). The horizontal tubes are large volume reactors with productivity similar to that of open ponds, but result in an MBSP of $708/ton AFDW. The helical tubes are made from glass and have a high capital investment resulting in a MBSP of $1,737/ton AFDW. The GWP-II PBR is a vertical flexible plastic flat-panel system with an estimated MBSP of $1,793/ton AFDW. Finally, the Leidos hanging bag system, which derives cultivation cost values based on inputs furnished by Algenol, results in an estimated MBSP of $639/ton AFDW.