Dynamic Metabolic Model Building Based on the Ensemble Modeling Approach [electronic resource]

• Ngôn ngữ: eng
• Ký hiệu phân loại: 666.3 Pottery
• Thông tin xuất bản: Washington, D.C. : Oak Ridge, Tenn. : United States. Dept. of Energy. Office of Science ; Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy, 2016
• Mô tả vật lý: Size: 8 p. : , digital, PDF file.
• Bộ sưu tập: Metadata
• ID: 264579
• Chủ đề: 1. 09 biomass fuels; 2. Bifurcational robustness; 3. E.coli; 4. Entropy index; 5. Isobutanol production

Tóm tắt

Ensemble modeling of kinetic systems addresses the challenges of kinetic model construction, with respect to parameter value selection, and still allows for the rich insights possible from kinetic models. This project aimed to show that constructing, implementing, and analyzing such models is a useful tool for the metabolic engineering toolkit, and that they can result in actionable insights from models. Key concepts are developed and deliverable publications and results are presented.