The Genomic Science program of the Office of Biological and Environmental Research (BER) within the U.S. Department of Energy (DOE) Office of Science focuses on understanding microbes, microbial communities, and plants as integrated systems of relevance to DOE?s energy and environmental missions. One aspect of the program seeks to develop the fundamental science, research technologies, and knowledgebase necessary to enable the cost-effective, sustainable production of biofuels and bioproducts from plant biomass. This initial potential of biomass was outlined in the Billion-Ton Study (U.S. DOE 2005
update, U.S. DOE 2011a). Achieving multiple societal benefits underlies DOE?s research efforts to support a viable and sustainable domestic lignocellulosic advanced biofuels and bioproducts industry. These benefits include ensuring future energy security, lowering greenhouse gas production to mitigate climate impacts, diversifying the range of available biobased products, producing less toxic chemicals and byproducts, creating jobs in rural areas, and improving the U.S. trade balance. An earlier DOE workshop sought ways to realize these benefits by accelerating the emergence of a robust, new cellulosic ethanol industry. The resulting report, Breaking the Biological Barriers to Cellulosic Ethanol (U.S. DOE 2006), outlined a path toward this future, emphasizing integrated research opportunities, from feedstock development to conversion technologies.