To make biomass more accessible for enzymatic hydrolysis, lime pretreatment of <
em>
Miscanthus giganteus<
/em>
with oxidants was explored from 100 to 150 �C. Composition data for the recovered solid were obtained to determine the effects of the reaction time, lime dosage, oxidant loading, and temperature on sugar production efficiency. Under selected conditions (0.2 g of lime/g of biomass, 200 psig O<
sub>
2<
/sub>
, and 150 �C for 1 h), delignification was 64.7%. The pretreated biomass was then followed by enzymatic hydrolysis. Furthermore, the yield of cellulose in the recovered solid to glucose was 91.7% and hemicellulose to xylose was 67.3%, 7.1 and 18.2 times larger than those obtained from raw biomass, respectively. Pretreatment with oxidants substantially raised delignification of raw <
em>
M. giganteus<
/em>
, thereby enhancing enzymatic hydrolysis to sugars, while results were not improved when pretreatment included ammonium molybdate.