This volume covers an array of techniques available for studying peptide-protein docking and design. The book is divided into four sections: peptide binding site prediction
peptide-protein docking
prediction and design of peptide binding specificity
and the design of inhibitory peptides. The chapters in Modeling Peptide-Protein Interactions: Methods and Protocols cover topics such as the usage of ACCLUSTER and PeptiMap for peptide binding site prediction
AnchorDock and ATTRACT for blind, flexible docking of peptides to proteins
flexible peptide docking using HADDOCK and FlexPepDock
identifying loop-mediated protein-protein interactions using LoopFinder
and protein-peptide interaction design using PinaColada. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary details for successful application of the different approaches and step-by-step, readily reproducible protocols, as well as tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Modeling Peptide-Protein Interactions: Methods and Protocols provides a diverse and unified overview of this rapidly advancing field of major interest and applicability.-- Source other than the Library of Cong
Includes bibliographical references and index