Cell Motility in Cancer Invasion and Metastasis [electronic resource]

• Tác giả: Alan Wells
• ISBN-13: 978-1402040092
• Ký hiệu phân loại: 571.978 +Tumors
• Thông tin xuất bản: Dordrecht : Springer Netherlands : Imprint: Springer, 2006.
• Mô tả vật lý: XIII, 353 p. , online resource.
• Bộ sưu tập: Tài liệu truy cập mở
• ID: 289387
• Chủ đề: 1. Biology-Research; 2. Cancer; 3. Life sciences; 4. Medicine-Research; 5. Oncology

Tóm tắt

Cancer Morbidity and mortality result from invasive and metastatic spread. Currently, no therapies are aimed at the underlying mechanisms that enable this progression due to only nascent recognition of the distinct biology which occurs only during tumor dissemination. Recent advances have highlighted the central role of cell motility during the dynamic and transient process of tumor invasion and metastasis. This book includes state-of-the-art updates by international leaders in these studies.
- Chapter s first present the novel model systems that enable new investigations and insights.
- Chapter s then describe in depth the key processes and molecules that may be therapeutically targeted. Finally, the role of cell motility and its signals is explored in a number of key tumor types. This compilation should be useful to researchers in basic and translational oncology as well as those developing novel agents to prevent tumor invasion and metastasis.