Cell Adhesion and Cytoskeletal Molecules in Metastasis [electronic resource]

• Tác giả: Anne E Cress, Raymond B Nagle
• ISBN-13: 978-1402051296
• Ký hiệu phân loại: 617 Miscellaneous branches of medicine Surgery
• Thông tin xuất bản: Dordrecht : Springer Netherlands : Imprint: Springer, 2006.
• Mô tả vật lý: XII, 196 p. , online resource.
• Bộ sưu tập: Tài liệu truy cập mở
• ID: 289561
• Chủ đề: 1. Biology-Research; 2. Cancer; 3. Dermatology; 4. Medicine-Research; 5. Surgery

Tóm tắt

 In this volume, the expression of specific adhesion molecules within human cancer tissues are highlighted. The expression signatures from published DNA microarray and immunohistochemistry studies are detailed. The concept that the alteration of specific adhesion molecules influence the cancer migration ability and cancer damage responses is detailed in this volume
  both features are essential for the survival of an invading tumor cell. Defining the minimal adhesion receptors preserved on cancer cells during tumor progression will define the metastatic adhesion signature. Understanding the metastatic adhesion signature will reveal vulnerabilities that could be exploited for the prevention and/or eradication of the invading cancer cell.