Calcium Handling in hiPSC-Derived Cardiomyocytes [electronic resource]

• Tác giả: Siu Chung-Wah, Lee Yee-Ki
• ISBN-13: 978-1461440932
• Ký hiệu phân loại: 571.6 Cell biology
• Thông tin xuất bản: New York, NY : Springer New York : Imprint: Springer, 2012.
• Mô tả vật lý: XII, 52 p. 18 illus., 17 illus. in color. , online resource.
• Bộ sưu tập: Tài liệu truy cập mở
• ID: 291507
• Chủ đề: 1. Cardiology; 2. Cytology; 3. Stem cells; 4. Stem Cell Biology

Tóm tắt

Calcium is crucial in governing contractile activities of myofilaments in cardiomyocytes, any defeats in calcium homeostasis of the cells would adversely affect heart pumping action. The characterization of calcium handling properties in human induced pluripotent stem cell-derived cardiomyocytes (iPS-CMCs) is of significant interest and pertinent to the stem cell and cardiac regenerative field because of their potential patient-specific therapeutic use.