To continue monitoring how the Coronavirus (COVID-19) pandemic has affected the welfare of households in the region, the World Bank and the United Nations Development Programme (UNDP) joined forces in 2021 to implement a second phase of High-Frequency Phone Surveys (HFPS) in Latin America and the Caribbean (LAC). A first wave was collected between May and July 2021, and a second between October 2021 and January 2022. This last wave takes the socio-economic pulse of households and measures the region's well-being almost two years into the pandemic. This note presents the emerging results in the areas of labor markets, income, food security, coping mechanisms, education, health, and gender.