KHẢO SÁT NGUYÊN NHÂN GÂY NHIỄM TRÙNG VẾT THƯƠNG VÀ ĐÁNH GIÁ KHẢ NĂNG KHÁNG KHÁNG SINH CỦA VI KHUẨN Staphylococcus aureus tại BỆNH VIỆN QUÂN Y 175

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Thông tin xuất bản: Tạp chí Khoa học Công nghệ và Thực phẩm (Tên mới: Tạp chí Khoa học Đại học Công Thương), 2020

Mô tả vật lý: tr.112

Bộ sưu tập: Metadata

ID: 294181

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Surgical site infection is one of the common types of hospital infections
it significantly limits the effectiveness of surgical interventions, increases the cost of treatment, and prolongs the duration of treatment. Staphylococcus aureus (S. aureus) is currently the most common cause of infection in hospitalized patients and it is also the most antibiotic-resistant bacteria. In this study, a total of 442 specimens from surgical patients treated at 175 Military Hospital including fluid, pus was collected and analyzed. In which, the infection rate caused by S. aureus bacteria accounts for 15.2%. The isolated S. aureus were resistant to 7 types of antibiotics, namely: penicillin100%
oxacillin 76.1%
erythromycin 65.7%
cefalexin 67.7%
getamycin 35.8%
ciprofloxacin 28.3%, and vancomycin 7.5%. No sequence variation in mecA genes of S. aureus in this study was found
however, there was a difference in mecA gene sequence among samples in this study compared to mecA gene of S. aureus of different countries around the world. The results of this study could be beneficial for further studies of the relationship between mecA gene sequence and antibiotic resistance of S. aureus bacteria.Vi khuẩn Staphylococcus aureus (S. aureus) là đối tượng gây nhiễm trùng thường gặp nhất ở bệnh viện và đây cũng là loài vi khuẩn có khả năng kháng kháng sinh mạnh nhất. Trong nghiên cứu ngày, tổng cộng 442 mẫu bệnh phẩm từ các bệnh nhân được điều trị tại Bệnh viện Quân Y 175 bao gồm dịch, mủ được thu thập và phân tích. Trong đó, tỷ lệ nhiễm trùng do vi khuẩn S. aureus chiếm 15,2%. Các mẫu vi khuẩn S. aureus thu được sau đó được xác định có khả năng kháng lại 7 loại kháng sinh, gồm: penicillin100%
oxacillin 76,1%
erythromycin 65,7%
cefalexin 67,7%
getamycin 35,8%
ciprofloxacin 28,3%, và vancomycin 7,5%. Kết quả phân tích không tìm ra sự khác biệt trong trình tự gene mecA của 9 mẫu S. aureus, nhưng có sự khác biệt về trình tự gene này giữa các mẫu trong nghiên cứu so với gene mecA của S. aureus ở các nước trên thế giới. Kết quả nghiên cứu này là tiền đề để nghiên cứu sâu hơn mối liên quan giữa trình tự gene mecA và khả năng kháng kháng sinh của vi khuẩn S. aureus.

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