This note provides an overview of the situation of LGBTI people globally and why addressing discrimination against them and promoting their inclusion make economic sense as well as being the right thing to do. It lays out the authorizing environment for SOGI inclusion at the World Bank and highlights promising practices of SOGI inclusion, including in data generation and operations from the World Bank and public and private sector partners. The note highlights opportunities to advance SOGI inclusion through the three strategic objectives of the World Bank's Gender Strategy update, namely ending gender-based violence and elevating human capital, expanding and enabling economic opportunities, and engaging women as leaders. The World Bank and development partners can also better integrate SOGI inclusion in their work on gender data generation, evaluation and learning, policy and institutional reforms, and capacity building.