High-frequency phone surveys conducted in 13 countries in Latin America and the Caribbean (LAC) show that women were 44 percent more likely than men to lose their jobs at the onset of Coronavirus disease 2019 (COVID-19). As the crisis evolved, temporarily unemployed workers started to go back to work. But the difference in job losses among women and men persisted. Also, highly female-intensive sectors - trade, personal services, education, and hospitality - explain 56 percent of all job losses. And the presence of school-age children at home is linked with a rise in job losses among women, but not among men.