Fragility, Conflict, and Violence (FCV) affects women, men, girls, and boys differently. FCV tends to exacerbate gender disparities in education, health, economic participation, voice, and agency. The number of people living in FCV settings is at a record high due to ongoing and new conflicts. FCV countries make up the ten worst-performing countries on several indicators that are critical for gender equality, including maternal mortality, school enrollment, and reproductive health care. There are several existing processes and instruments that task teams can draw on to maximize gender outcomes in FCV contexts. The objective of this approach paper is to identify practices and approaches in the design, implementation, monitoring, and measuring of interventions and operations that respond to the differentiated needs of women, girls, men, and boys, and contribute towards addressing gender inequalities in FCV countries. The approach paper features selected operational highlights showcasing regional experiences, lessons learned, and best practices on addressing gender inequalities in FCV settings. Additionally, it includes an action plan outlining steps to elevate gender issues and responses beyond individual projects to more strategic country engagements.