Blockchain and other trustless systems have gone from being relatively obscure technologies, which were only known to a small community of computer scientists and cryptologists, to mainstream phenomena that are now considered powerful game changers for many industries. This book explores and assesses real-world use cases and case studies on blockchain and related technologies. The studies describe the respective applications and address how these technologies have been deployed, the rationale behind their application, and finally, their outcomes. The book shares a wealth of experiences and lessons learned regarding financial markets, energy, SCM, healthcare, law and compliance. Given its scope, it is chiefly intended for academics and practitioners who want to learn more about blockchain applications.