Despite Ghana's growth in the last several decades, regional, demographic, and social inequalities have exacerbated marginalization and exclusion, leaving vulnerable groups exposed to exogeneous economic and social shocks. With Coronavirus (COVID-19) and the resultant economic slowdown, the poverty level is likely to rise in 2021 to 30.9 percent, compounding further inequalities and vulnerabilities and expanding pressure on public funds to respond. To assess the progression of these exclusion disparities, the World Bank has developed the Social Sustainability and Inclusion (SSI) profile. This SSI note is meant to deepen analysis and provide a snapshot of the social sustainability and inclusion landscape in Ghana.