Characterization of Protein Therapeutics using Mass Spectrometry [electronic resource]

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Tác giả: Guodong Chen

Ngôn ngữ:

ISBN-13: 978-1441978622

Ký hiệu phân loại: 543.65 Mass spectrometry (Mass spectroscopy)

Thông tin xuất bản: New York, NY : Springer US : Imprint: Springer, 2013.

Mô tả vật lý: X, 404 p. , online resource.

Bộ sưu tập: Tài liệu truy cập mở

ID: 309237

Protein therapeutics' high efficacy, safety, and ability to treat life-threatening diseases such as cancer, inflammation and genetic disorders have revolutionized modern medicine. In 2012, 200 companies competed in this $90 billion year industry.   In Characterization of Protein Therapeutics using Mass Spectrometry, expert contributors from academia and industry highlight current approaches and future trends. The book discusses mass spectrometry techniques as related to the analysis of protein therapeutics, structural identification strategies and quantitative approaches. The book also covers various studies involving characterization of process related protein drug impurities/degradants, metabolites, PTMs and  higher order structures of protein therapeutics.   General practitioners in pharmaceutical research, specialists in analytical sciences, and graduate students studying mass spectrometry and pharmaceutical sciences will find this book useful because of  the  step-by-step approaches and new strategies to solve challenging problems related to protein therapeutics research and development.
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