Biomaterials in Regenerative Medicine and the Immune System [electronic resource]

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Tác giả: Laura Santambrogio

Ngôn ngữ:

ISBN-13: 978-3319180458

Ký hiệu phân loại: 620.19 Other engineering materials

Thông tin xuất bản: Cham : Springer International Publishing : Imprint: Springer, 2015.

Mô tả vật lý: IX, 280 p. 82 illus., 59 illus. in color. , online resource.

Bộ sưu tập: Tài liệu truy cập mở

ID: 310027

The generation of tridimensional tissues, assembled from scaffolding materials populated with biologically functional cells, is the great challenge and hope of tissue bioengineering and regenerative medicine. The generation of biomaterials capable of harnessing the immune system has been particularly successful. This book provides a comprehensive view of how immune cells can be manipulated to suppresses inflammation, deliver vaccines, fight cancer cells, promote tissue regeneration or inhibit blood clotting and bacterial infections by functionally engineered biomaterials. However, long-lived polymers, such as those employed in orthopedic surgery or vascular stents, can often induce an immune reaction to their basic components.  As a result, this book is also an important step towards coming to understand how to manipulate biomaterials to optimize their beneficial effects and downplay detrimental immune responses. Dr. Santambrogio is Professor of Pathology, Microbiology and Immunology and Orthopedic Surgery at the Albert Einstein College of Medicine. She received her M.D. from the University of Perugia and her Ph.D. from the University of Padua in Italy. She received her postdoctoral training at NYU and Harvard Medical School. One of the focuses of the research in her laboratory is the understanding of the immune responses to implanted biomaterials.  .
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