EXTRACTION OF TAMANU OIL FROM Calophyllum inophyllum L. SEEDS BY ULTRASOUND-ASSISTED METHOD AND TESTING WOUND CARE TREATMENT

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Tác giả: Minh Nam Hoang, Khanh Duy Huynh, Thi Mong Thy Lu, Thanh Phong Mai, Duc Viet Nguyen, Huu Hieu Nguyen, Le Thao My Phan, Do Dat Tran, Le Khoi Truong, Hoai Thanh Vuong

Ngôn ngữ: eng

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Thông tin xuất bản: Tạp chí Khoa học Công nghệ và Thực phẩm (Tên mới: Tạp chí Khoa học Đại học Công Thương), 2020

Mô tả vật lý: tr.54

Bộ sưu tập: Metadata

ID: 313024

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Tamanu oil was extracted from Calophyllum inophyllum Linn. by ultrasound-assisted method. Four solvents including n-hexane, ethanol, petroleum ether, and ethyl acetate were investigated. Response surface methodology was employed to investigate effects of time, temperature, and solvent-to-material ratio on the extraction yield. Tamanu oil extraction yield was achieved of 55.15% under conditions including time of 23 minutes, temperature of 42 °C, solvent-to-material ratio of 26 to 1 (v/w) mL/g. In addition, better physicochemical indices and similar fatty acid components compared to that of commercial oil were reported indicating the quality of the extracted oil. Wound healing abilities of the extracted tamanu oil was also tested on Swiss albino mice and a commercial product showing the potential agent for wound care treatment of tamanu oil based on the recorded better wound healing ability.Keywords: Tamanu, ultrasound, response surface methodology, Box-Hunter, wound healingTrong nghiên cứu này, dầu trích ly từ hạt mù u (Calophyllum inophyllum Linn.) với sự hỗ trợ của sóng siêu âm. Đánh giá khả năng trích của 4 loại dung môi bao gồm n-hexane, ethanol, ether dầu hỏa, và etyl acetat
và sử dụng phương pháp bề mặt đáp ứng để khảo sát ảnh hưởng đồng thời của các yếu tố gồm thời gian, nhiệt độ, tỷ lệ dung môi:nguyên liệu đến hiệu suất quá trình trích ly dầu mù u. Điều kiện tối ưu được xác định tại 23 phút, 42 °C, tỷ lệ dung môi:nguyên liệu 26:1 (v/w) mL/g với hiệu suất trích ly đạt là 55,15%. Bên cạnh đó, các chỉ tiêu hóa lý của dầu mù u thu được cao hơn và thành phần axit béo tương đồng với một sản phẩm thị trường. Ngoài ra, khả năng chữa lành vết thương của dầu mù u trích ly được thử nghiệm trên chuột Swiss albino tốt hơn sản phẩm thị trường. Vì vậy, dầu mù u trích ly trong nghiên cứu có tiềm năng sử dụng trong điều trị vết thương.Từ khóa: Dầu mù u, siêu âm, phương pháp bề mặt đáp ứng, làm lành vết thương.

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