Afghanistan is a deeply fragile and conflict affected state. It has been in almost constant conflict for over 35 years since the Soviet invasion of 1979. Today the country is at a crossroads in its development with economic growth down sharply and poverty incidence stubbornly high. Afghanistan faces tremendous development challenges. Gross domestic product (GDP) per-capita is among the lowest in the world, poverty is deep and widespread, and social indicators are still at very low levels. The new government has declared its commitment to address Afghanistan's development challenges, through its paper realizing self-reliance: commitments to reforms and renewed partnership presented at the London conference in December 2014. The purpose of this systematic country diagnostic (SCD) is to provide an evidence-based diagnostic within an objective framework to help in the identification of development priorities. Countries in conflict often face rapidly evolving circumstances and flexibility to adjust quickly is a necessity. The SCD is thus intended to set forth a broad and flexible framework for thinking about choices, prioritization, and sequencing.