The reforms of the Colombian Health System in the last decade have sought to position primary health care (PHC) as an essential strategy to guarantee integrated and comprehensive care of the population's health needs. The Primary Health Care approach includes three integrated, interdependent components: health services, intersectoriality, and social participation in terms of empowering individuals, families and communities to take charge of their own health. Within this conceptual framework, Colombia has tackled the SARS CoV-2 (COVID-19) pandemic formally announcedby the World Health Organization (WHO) on March 11, 2020. This report examines the role of PHC in Colombia›s preparation for, response to, and recovery from the pandemic. The main features of the pandemic affecting the country are described first, followed by observations stemming from analysis of the regulatory component, the healthcare services delivered, and the role of public health communication and surveillance. The report ends with conclusions on the analysis.