In developing countries, urbanization and rapid population growth have resulted in a dramatic increase in Municipal Solid Waste (MSW) generation. Safe collection, transportation, and treatment of MSW are among the major issues for Quang Binh province. Improper MSW management (MSWM) practices can have adverse effects on human health, the environment, and climate change. This paper reviews the existing MSWM practices, challenges and provides suggestions to help improve the MSWM system in Quang Binh province. This study also presents an assessment of the existing situation of MSWM in Quang Binh province. The results show that the municipal solid waste collection network has not covered the major part of the concentrated residential areas. The daily collection rate is only about 78.56% in the places where the collection network has reached. Landfills are currently the most common method of MSW treatment while most waste treatment plants (WTPs) have not generated electricity yet. Moreover, the amount of MSW sent to landfills just accounted for over 50% of the waste brought to the WTPs. In order to improve the efficiency of solid waste management system and to optimize the operation of the waste collection vehicles following the conditions of the province, the use of information technology was proposed to apply to the collection management system. Conversely, in the long term, it is necessary to implement separation of waste at source to reduce the pressure on the WTPs and develop more associated technologies such as waste-to-energy technology. These technologies will enable the WTPs to enhance the flexibility of their treated products as well as introduce these products into the markets.