Objectives: To describe work motivation and related factors among nurses at Thai Binh Traditional Medical Hospital in 2021. Methods: Quantitative and qualitative research were conducted on 88 nurses working at Thai Binh traditional medicine hospital. The quantitative data was collected by using the questionnaire from 88 nurses, and the qualitative data was collected by using In-depth interview guideline from 10 nurses at ten wards. Results: Percentage of nurses who are motivated to work with factors such as commitment to the organization (72.7%), nature of work (62.5%), work benefits (54.5 %), working relationship (43.2%). Factors related to the work motivation of nurses are: age, income
work experience
direct manager
governance and operations of the organization
peer relationships
the stability and safety of workers
hospital policy. Conclusions: The work motivation score was 4.0, 53.4% of nurses had work motivation. Age, working experience, average income, wages, and extra incomes, direct manager, policy regime, co-operative relations, safety in work were fators which associated with a work motivation statistically significant at p <
0.05.