The development of HPLC dual wavelength fluorescence detection method for the simultaneous determination of four fluoroquinolones in human plasma

• Tác giả: Dien Xuan Luong, Thi Minh Nguyen Diep, Xuan Nguyen Truong, Tuan Anh Vu
• Ngôn ngữ: eng
• Thông tin xuất bản: Vietnam Journal of Science, Technology and Engineering - C, 2022
• Mô tả vật lý: tr.16
• Bộ sưu tập: Metadata
• ID: 331424

Tóm tắt

A high-performance liquid chromatography-fluorescence detection (HPLC-FLD) method for determination of the fluoroquinolones norfloxacin (NOR), ciprofloxacin (CIP), levofloxacin (LEVO), and moxifloxacin (MOXI) in human plasma has been successfully developed. The detection was optimized with a dual wavelength excitation and emission fluorescence detector. Analytical wavelengths of λex/λem = 290/500 nm (for LEVO and MOXI)...