In silico screening of chalcones and their derivatives as potential inhibitors of spike proteins and ACE2 enzymes for SARS-CoV-2 treatment

• Tác giả: Kim Nguyen Bao, Tung Bui Thanh, Hong Khanh Do Thi, Thu Hang Ta Thi
• Ngôn ngữ: eng
• Thông tin xuất bản: Vietnam Journal of Science, Technology and Engineering - C, 2022
• Mô tả vật lý: tr.69
• Bộ sưu tập: Metadata
• ID: 331434

Tóm tắt

The COVID-19 pandemic causing acute respiratory syndrome is a significant public health problem. Drugs that can treat this disease are currently a high priority. The SARS-CoV-2 spike protein and human ACE2 enzyme receptor, which both play important roles in virus entry into the host cell, are promising therapeutic targets for inhibiting viral infection...