ĐÁNH GIÁ HOẠT TÍNH KHÁNG KHUẨN CỦA CAO CHIẾT RAU SAM (PORTULACA OLERACEA) THU TẠI THÁI NGUYÊN

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Tác giả: Mạnh Sơn Đỗ, Phú Hiệp Hoàng, Thu Thảo Hoàng, Phú Hùng Nguyễn, Trọng Tấn Nguyễn, Văn Khang Phạm

Ngôn ngữ: vie

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Thông tin xuất bản: Tạp chí Khoa học và Công nghệ - Đại học Thái Nguyên, 2022

Mô tả vật lý: tr.126-131

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ID: 332159

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Portulaca oleracea is a vegetable that grows in wet wild places in our country. Portulaca oleracea contains many proteins, sterols, carotenoids and polysaccharides. Furthermore, it has many vitamins (A, C, E, and some B-complexes) and minerals (Ca, Fe, Mn, P, and Se). So, Portulaca oleracea is used as food but also as a medicine. In traditional medicine, Portulaca oleracea is used as a medicine for diarrhea, acne, diuretic, and deworming. In this study, Portulaca oleracea extract was used to chemical composition determination by color reaction and evaluate antibacterial activity. After reflux extraction, 90 g of ethanol extract and 30 g of dichloromethane extract were collected. The results show that the ethanol extracts and dichloromethane extract of Portulaca oleracea have phenolic, alkaloid, flavonoid, steroid groups. Alcohol and dichloromethane extracts of Portulaca oleracea have strong antibacterial ability, in which dichloromethane extract concentration of 100 mg/mL has the best bactericidal ability. Research results show the potential of Portulaca oleracea to replace antibiotics in human disease prevention.Rau sam (P. oleracea) là loại rau mọc hoang ở khắp những nơi ẩm ướt của nước ta. Trong Rau sam có chứa nhiều protein, sterol, carotenoid và polysaccharid. Nhiều loại vitamin (A, C, E và một số phức-B) và khoáng chất (Ca, Fe, Mn, P và Se). Vì vậy, Rau sam không chỉ được sử dụng làm thức ăn mà còn dùng như một vị thuốc. Trong dân gian, Rau sam làm thuốc chữa bệnh lỵ trực tràng, giã nát đắp mụn nhọt, làm thuốc lợi tiểu, tẩy giun kim. Trong nghiên cứu này, cao chiết Rau sam được xác định thành phần hoá học và đánh giá hoạt tính kháng khuẩn. Bằng phương pháp chiết hồi lưu đã thu được 90 g cao ethanol và 30 g cao dichloromethane. Kết quả cho thấy đã xác định được trong cao chiết ethanol và cao dichloromethane của cây Rau sam đều có các nhóm phenolic, alkaloid, flavonoid, coumarin, steroid. Cao chiết ethanol và dicloromethan Rau sam có khả năng kháng khuẩn mạnh, trong đó cao chiết dicloromethan nồng độ 100 mg/mL có khả năng diệt khuẩn tốt nhất. Kết quả nghiên cứu cho thấy tiềm năng của cây Rau sam có thể thay thế kháng sinh trong phòng trị bệnh do vi khuẩn gây ra ở người.

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