KẾT QUẢ CHUYỂN PHÔI GIAI ĐOẠN PHÔI PHÂN CHIA VÀ GIAI ĐOẠN PHÔI NANG TRONG HỖ TRỢ SINH SẢN

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Tác giả: Thị Nhàn Dương, Hải Bằng Hà, Minh Tuân Hứa, Thị Thanh Hương Lê, Phú Hùng Nguyễn

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Khoa học và Công nghệ - Đại học Thái Nguyên, 2022

Mô tả vật lý: tr.308-317

Bộ sưu tập: Metadata

ID: 332186

Thêm vào giỏ Liên kết toàn văn

Lựa chọn phôi có tiềm năng phát triển cao để chuyển và đạt được một ca sống khỏe mạnh là mục đích của hỗ trợ sinh sản. Tại các Trung tâm Hỗ trợ sinh sản khác và tại khoa Hỗ trợ sinh sản - Bệnh viện A Thái Nguyên, việc chuyển phôi ngày 3 và ngày 5 vẫn được tiến hành song song và phụ thuộc vào đặc điểm của từng bệnh nhân. Mục tiêu chính của nghiên cứu này là đánh giá kết quả chuyển phôi được xếp loại phôi tốt ở giai đoạn phôi phân chia (ngày 3) và giai đoạn phôi nang (ngày 5) bằng phương pháp nghiên cứu hồi cứu dựa trên các tiêu chí về chất lượng phôi chuyển, kết quả beta HCG sau chuyển phôi, tỷ lệ thai lâm sàng, thai sinh hóa, thai diễn tiến. Kết quả nghiên cứu đã chỉ ra rằng tỷ lệ beta dương là 60,9%
tỷ lệ thai lâm sàng là 56,4%
tỷ lệ thai diễn tiến là 55,0%. Bên cạnh đó, tỷ lệ thai diễn tiến thấp hơn đáng kể ở nhóm bệnh nhân thực hiện chuyển phôi ngày 3 so với nhóm chuyển phôi ngày 5 (47,9% so với 86,5%) nhưng tỷ lệ đa thai khi chuyển phôi ngày 5 lại cao hơn so với chuyển phôi ngày 3 (31,5% với 8,5%). Như vậy, chuyển phôi ở giai đoạn phôi nang có ưu thế hơn so với chuyển phôi ở giai đoạn phôi phân chia được đánh giá ở nghiên cứu này của chúng tôi.Selecting the high developmental potential embryos to transfer and achieving a healthy live birth is the goal of assisted reproduction. At other Assisted Reproductive Centers and at the Department of assisted reproductive technology - A Thai Nguyen hospital, day 3 and day 5 embryo transfers are still carried out in parallel and depend on the characteristics of each patient. The objective of this study was to evaluate the result of embryo transfer which was good at the cleavage embryo stage (day 3) and blastocyst stage (day 5) with using a retrospective study method based on the criteria of embryo transfer quality, beta HCG results after embryo transfer, clinical pregnancy rate, biochemical pregnancy, progressed pregnancy. Our study showed that the rate of beta positive is 60.9%, the rate of a clinical pregnancy is 56.4%, the rate of ongoing pregnancy is 55.0%. In addition, the rate of ongoing pregnancy was significantly lower in the group of patients undergoing day 3 embryo transfer compared with day 5 embryo transfer (47.9% vs 86.5%), but the rate of multiple pregnancies at day 5 embryo transfer was higher than that of day 3 embryo transfer (31.5% vs 8.5%). Curently, embryo transfer at blastocyst stage has an advantage over cleavage embryo transfer which was evaluated in our study.

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