FABRICATION AND CHARACTERIZATION OF CELLULOSE DERIVATIVES-BASED HYDROGEL

0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Ngoc Ha Giang, Nguyen Anh Tuan Huynh, Thi Kim Anh Le, Thi Phuong Dung Truong

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Khoa học Công nghệ và Thực phẩm (Tên mới: Tạp chí Khoa học Đại học Công Thương), 2022

Mô tả vật lý: tr.80

Bộ sưu tập: Metadata

ID: 333372

Thêm vào giỏ Liên kết toàn văn

Hydrogel materials have been extensively studied by many research groups owing to their wide application. The green approach in hydrogel fabrication might include polymers from natural sources. Cellulose derivative is a potential candidate because of its biocompatibility and readily availability. In this study, hydroxypropyl methyl cellulose (HPMC), hydroxypropyl cellulose (HPC), hydroxyethyl cellulose (HEC) and sodium carboxymethyl cellulose (CMC or NaCMC) shall be crosslinked with glutaraldehyde to confirm the ability to fabricate the cellulose-based hydrogel. The investigation showed that HPMC was not suitable for hydrogel fabrication due to low gel-time signal and small gel fraction (~10%). The gel time signal could be detected with only CMC solution. Accordingly, the CMC sample had the highest gel fraction (89%). CMC and HEC were comparable in water uptake (80 to 120%). HPC solution could be gelled at a higher concentration of glutaraldehyde and a completely gelled state of 100% gel fraction could be achieved. However, significantly large water uptake (up to 2000%) was detected with HPC - based samples.Vật liệu hydrogel đã được nghiên cứu chuyên sâu bởi nhiểu nhóm nghiên cứu nhờ vào tiềm năng ứng dụng rộng rãi của chúng. Phương pháp tiếp cận xanh trong quá trình chế tạo hydrogel là sử dụng các polymer có nguồn gốc tự nhiên. Dẫn xuất của cellulose là ứng cử viên tiềm năng bởi vì tính tương thích sinh học và dễ dàng tiếp cận. Trong nghiên cứu này, hydroxypropyl methyl cellulose (HPMC), hydroxypropyl cellulose (HPC), hydroxyethyl cellulose (HEC) và sodium carboxymethyl cellulose (CMC or NaCMC) sẽ được nối ngang bằng glutaraldehyde để xác nhận khả năng chế tạo hydrogel trên nền cellulose. Khảo sát cho thấy HPMC không thích hợp do tín hiệu đo đạc thời gian gel thấp và hàm lượng gel nhỏ (~10%). Dung dịch CMC là mẫu duy nhất cho tín hiệu thời gian gel và có hàm lượng gel cao nhất (89%). CMC và HEC có độ hấp thụ nước tương đồng nhau (80-120%). HPC chỉ có thể hình thành gel (khâu mạng) với hàm lượng glutaraldehyde cao hơn và trạng thái hoàn toàn gel (100% hàm lương gel) có thể đạt được. Tuy nhiên, lượng lớn nước hấp thụ (lên đến 2000%) đã được xác nhận với các mẫu trên nền HPC.

1. Đọc trực tuyến

1. Đọc trực tuyến

Tạo bộ sưu tập với mã QR