Culture is a major element in doing business. Today’s globalisation has been impacting the world economy and increased the importance of cross-cultural business transactions. While trade and technology practices are breaking down physical barriers, cultural issues are emerging as the new barriers for business. Cultural barriers are like icebergs that can cause misunderstandings and collisions during business transactions (Gupta, S. and Bhaskar, A. U. , 2016). This paper is an attempt to understand Indian and Vietnamese business cultures through the cultural dimensions proposed by Geert Hofstede. The cultural dimensions of Hofstede are significant in finding similarities and differences between the business practices and negotiation and leading styles of India and Vietnam. By using Hofstede’s cultural dimensions in analysing the similarities and differences of Indian and Vietnamese business cultures, the paper hopes to contribute to better understanding both countries’ business cultures which will eventually help promote bilateral economic relations.