The Palaeolithic industry in the Bose (Baise) Basin, Guangxi, South China, is well-known in the international scientific community for its handaxes dating back to the early Middle Pleistocene. In recent years, a bifacial industry has been discovered in An Khe, Gia Lai Province, located towards the southern part of Vietnam, which has been dated to 806ka BP. The Bose and An Khe bifacial industries are important in the study of Lower Palaeolithic cultures of East and Southeast Asia. This paper presents a comparison of these two industries, and discusses some related issues.