The scarcity of natural sand for construction in the current circumstance has made researchers and engineers search for another resource to replace it. This paper presents a study on the influence of crushed sand and natural sand on the properties of self-compacting concrete (SCC) implemented for the Dong Nan Ren irrigation project-Bac Lieu province. The experiment pointed out that at fresh state the SCC mixture with natural sand had shown better performance than that with crushed sand. In the meantime, both mixtures with crushed and natural sand have yielded the self-compacting properties (slump flow value and T500) in accordance with the requirement of the concerned project. Compressive and flexural strength at 28 days of the SCC with crushed sand are 10.1% and 21.9% respectively higher than that of the one with natural sand. Besides, both of them achieved the waterproof grade W6, which is suitable for construction of hydraulic structures. This outcome verifies that in case there is a lack of natural sand, the crushed sand can substantially replace it for the SCC production.