The research aims at providing background theory, depicting a clear picture of the Inquiry-based Learning approach through survey as well as interviews, and making some suggestions for more effective application to English-majored students at Ton Duc Thang University. The results of the survey demonstrate that students have positive attitudes towards this approach as it helps them enhance their learning autonomy, expertise knowledge, creative, and soft skills such as teamwork, critical thing skills, problem-solving skills, creative skills.. In addition, the interviews from students, lecturers, and managerial staff elicit that the Inquiry-based Learning approach is helpful in teaching and learning as it enables students to be more active in learning, doing research, and interacting between lecturers and students, which results in apparently better learning outcomes. Based on these practical surveys, this paper provides some implications of Inquiry-based Learning activities for English-majored students and English Language Teaching.