Tương quan giữa cắt lớp vi tính đánh giá độ sâu xâm lấn trong ung thư tế bào gai sàn miệng với mô bệnh học

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Tác giả: Minh Trí Cao, Anh Huy Nguyễn, Đại Hùng Linh Nguyễn, Tín Trung Nguyễn

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y Dược học Phạm Ngọc Thạch, 2023

Mô tả vật lý: tr.131

Bộ sưu tập: Metadata

ID: 339190

Thêm vào giỏ Liên kết toàn văn

- Mục tiêu nghiên cứu: Xác định mối tương quan trong đánh giá độ sâu xâm lấn (DOI) trong ung thư tế bào gai sàn miệng giữa cắt lớp vi tính (CT) và mô bệnh học.- Phương pháp nghiên cứu: Hồi cứu kết quả chụp CT trước phẫu thuật trên 19 bệnh nhân để đo DOI trên hai mặt phẳng sagital và coronal
sau đó so sánh với báo cáo mô bệnh học. DOI trung bình được so sánh giữa CT và mô bệnh học bằng phương pháp phân tích phương sai cho thí nghiệm tái đo lường. Độ mạnh của mối tương quan về độ sâu xâm lấn khối u giữa 2 phương pháp CT và mô bệnh học được xác định bằng hệ số tương quan, sau đó đánh giá độ chính xác bằng biểu đồ Bland - Altman.- Kết quả: Khi thực hiện đo đạc DOI trên CT có xu hướng cao hơn với kết quả mô bệnh học, với sự khác biệt trung bình là 0,684 mm trên mặt phẳng sagital và 1,474 mm trên mặt phẳng coronal. Về tương quan giữa độ sâu xâm lấn của khối u giữa CT và mô bệnh học, hệ số tương quan là 0,725 đối với mặt phẳng sagtial và 0,788 đối với mặt phẳng coronal. Phân tích bằng biểu đồ Bland - Altman cho thấy DOI khi đánh giá bằng CT và giải phẫu bệnh có sự tương đồng với nhau. - Kết luận: Mối tương quan tốt được xác định giữa cắt lớp vi tính và mô bệnh học với sự đồng thuận tốt
do đó chúng tôi đề nghị rằng độ sâu xâm lấn trên CT có thể dùng thay thế mô bệnh học trong đánh giá trước mổ.Abstract- Objectives: The aim of this study was to evaluate the correlation and accuracy of depth of invasion (DOI) measurement from preoperative contrast - enhanced computed tomography (CECT) scans in comparison to histopathological examination (HPE) in floor of mouth squamous cell carcinoma. - Methods: Preoperative CT scans of 19 patients were reviewed retrospectively to measure the DOI on sagital and coronal sections
these were then compared to the histopathological report. Mean DOI was compared between CECT and HPE using repeated measures ANOVA. The strength of correlation of CT - derived tumour depth was determined using the correlation coefficient followed by assessment of accuracy by Bland - Altman plot. - Results: In general, the measurement of DOI was higher on CECT, with a mean difference of 0,684 mm on sagital CT and 1,474 mm on coronal CT. Regarding the correlation between CECT and HPE tumour depth of invasion, correlation was 0,725 for sagital CT and 0,788 for coronal CT. Bland - Altman analysis showed that DOI from CECT and histopathological depth were in agreement with each other. - Conclusions: In conclusion, there was good correlation and accurate measurement of DOI from CECT. DOI: 10.59715/pntjmp.2.1.16

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