Khảo sát thành phần hóa học và điều kiện tách chiết Polyphenol, Flavonoid từ lá cây thạch vĩ (Pyrrosia lingua)

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Tác giả: Ngọc Khôi Phạm

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y Dược học Phạm Ngọc Thạch, 2023

Mô tả vật lý: tr.97

Bộ sưu tập: Metadata

ID: 339315

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Theo y học cổ truyền, lá cây thạch vĩ (Pyrrosia lingua) là một loại thảo dược quý dùng trong việc hỗ trợ điều trị viêm phế quản mạn tính, rụng tóc, giải độc lưu huỳnh. Mục tiêu nghiên cứu của đề tài nhằm xác định một số nhóm chất tự nhiên bằng phương pháp hóa học và khảo sát các yếu tố ảnh hưởng đến điều kiện tách chiết hàm lượng nhóm chất polyphenol, flavonoid tổng số từ lá cây thạch vĩ. Kết quả của nghiên cứu cho thấy có sự hiện diện của các nhóm chất tự nhiên quan trọng như polyphenol, flavonoid, tannin, alkaloid, steroid, nhưng không có nhóm chất saponin. Điều kiện tách chiết polyphenol, flavonoid tổng số từ lá cây thạch vĩ tối ưu nhất là dung môi methanol 80%, tỷ lệ nguyên liệu - dung môi là 1:10 (g/ml), thời gian chiết 120 phút, nhiệt độ chiết 60 °C. Nghiên cứu này đã xác định được một số nhóm chất tự nhiên và khảo sát được điều kiện chiết tách polyphenol, flavonoid tổng số tối ưu nhất từ lá cây thạch vĩ.Abstract According to traditional medicine, tongue fern (Pyrrosia lingua) is a preciousherb medicine, whose active ingredients might prevent many diseases such as chronic bronchitis, hair loss, sulfur detoxification. This study was conducted to demonstrate some natural compounds by chemical methods and investigate the factors affecting the extraction conditions of polyphenol, flavonoid compounds oftongue fern. Qualification of the natural compounds composition of tongue fernshowed in the presence of important natural compounds such as polyphenol, flavonoid, tannin, alkaloid, steroid, but no saponins. The most appropriate condition for extracting polyphenol, flavonoid compounds from tongue fernwas methanol 80%
the ratio of material and solvent was 1:10 (g/ml)
extraction time was 120 minutes
and temperature was 60 °C. A number of natural compounds have been identified and the best conditions for extracting polyphenol, flavonoid from tongue fern were investigated. DOI: 10.59715/pntjmp.1.2.11

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