Kết quả sớm điều trị ung thư biểu mô tế bào gan bằng vi sóng

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Tác giả: Xuân Bình Đậu, Trung Dũng Hồ, Hiền Thảo Ly Nguyễn, Vinh Quang Phạm, Thiện Lai Võ, Văn Hùng Võ

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y Dược học Phạm Ngọc Thạch, 2023

Mô tả vật lý: tr.166

Bộ sưu tập: Metadata

ID: 339323

Thêm vào giỏ Liên kết toàn văn

- Mở đầu: Ung thư biểu mô tế bào gan (UTBBTBG) là loại ung thư phổ biến hàng thứ bảy và gây tử vong xếp hàng thứ sáu trên tổng số trường hợp tử vong do ung thư. Hủy u bằng vi sóng bước đầu được ứng dụng tại BV Bình Dân để điều trị UTBMTBG. Nghiên cứu này đánh giá hiệu quả điều trị và sự an toàn của phương pháp hủy u bằng vi sóng (MWA) để điều trị UTBMTBG.- Phương pháp: Nghiên cứu hồi cứu thực hiện ở khoa Gan Mật Tụy Bệnh viện Bình Dân, 54 Bệnh nhân (BN) UTBMTBG (63 u: đường kính trung bình 24,5 ± 10,2mm, 10mm - 50mm) được điều trị bằng MWA. Tỷ lệ hủy u hoàn toàn, tái phát tại chỗ, xuất hiện khối u mới trong gan, các yếu tố liên quan tái phát được ghi nhận.- Kết quả: Không có tai biến, biến chứng nặng. Hủy u hoàn toàn sau 1 lần đốt là 82,9%, sau 2 lần đốt là 91,7%. Tỷ lệ tái phát tại chỗ là 9,5% trong 3 tháng và 14,46% sau 6 tháng. Các yếu tố: vị trí u khó, đường kính u trên 3cm, có sự liên quan có ý nghĩ thống kê với tái phát tại chỗ.- Kết luận: MWA an toàn và cho kết quả hủy u tại chỗ rất tốt.Abstract- Background: Hepatocellular carcinoma is the seventh most common cancer and the sixth leading cause of death out of all cancer deaths. Microwave ablation was initially applied at Binh Dan Hospital to treat HCC. This research evaluatedthe therapeutic effect and safety of microwave tumor destruction (MWA) for the treatment of HCC.- Methods: A retrospective study was performed at the Hepatobiliary and Pancreatic Department of Binh Dan Hospitalwith 54 patients with HCC (63 tumors: mean diameter of 24.5 ± 10.2mm, 10mm - 50mm) were treated with MWA. The rate of complete tumor destruction, local recurrence, appearance of new tumors in the liver,and the number of interventions per tumor were recorded.- Results: There were no serious complications. Complete tumor destruction after 1 burn is 82.9%, after 2 burns is 91.7%. The local recurrence rate was 9.5% at 3 months and 14.46% after 6 months. Factors: difficult tumor location and tumor diameter over 3cm had statistically significant association with local recurrence. - Conclusion: Medwave MWA is safe and efficient. This method showed the excelent locally detroying effectiveness on the treatment of HCCs. DOI: 10.59715/pntjmp.1.2.19

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