Đặc điểm chẩn đoán tiền sản và kết quả điều trị trẻ sơ sinh bị dị tật bẩm sinh đường tiêu hóa tại Bệnh viện Nhi Đồng 1

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Tác giả: Minh Xuân Ngô, Kiến Mậu Nguyễn, Văn Quang Nguyễn, Thị Hoài Thu Trần

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y Dược học Phạm Ngọc Thạch, 2023

Mô tả vật lý: tr.133

Bộ sưu tập: Metadata

ID: 339347

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- Đặt vấn đề: Mô tả đặc điểm chẩn đoán tiền sản và kết quả điều trị trẻ sơ sinh bị dị tật bẩm sinh đường tiêu hóa (DTBSĐTH) được phẫu thuật tại bệnh viện Nhi Đồng 1.- Đối tượng và phương pháp nghiên cứu: Cắt ngang mô tả. Đối tượng: Trẻ sơ sinh có chẩn đoán DTBSĐTH được phẫu thuật tại bệnh viện Nhi Đồng 1 từ 01/2020 đến 06/2021.- Kết quả: Ghi nhận có 205 trẻ sơ sinh bị DTBSĐTH được phẫu thuật. Tỷ lệ thai phụ được khám, tư vấn và chẩn đoán tiền sản là 100% (ở TP.HCM) và 95,6% (các tỉnh). Phương tiện chẩn đoán tiền sản phổ biến là siêu âm (97,6%). 42,5% phát hiện có DTBSĐTH bằng siêu âm tiền sản. 45,8% trẻ không được khám ngay sau sanh. 22,9% trường hợp điều trị thất bại rồi mới chuyển tuyến. Tuổi con lúc nhập viện trung bình 5,19 ngày tuổi. Thời gian nằm viện trung bình là 25,4 ngày. 48,8% có biến chứng. 77,1% trẻ xuất viện an toàn. Tỷ lệ tử vong 8,3%. So sánh giữa nhóm trẻ có mẹ được chẩn đoán tiền sản bị DTBSĐTH với nhóm trẻ còn lại tìm thấy sự khác biệt có ý nghĩa thống kê về tỷ lệ khám ngay sau sinh, lý do chuyển tuyến, thời điểm chuyển viện, đa dị tật bẩm sinh (DTBS) và bất thường NST, số ngày điều trị, tỷ lệ suy dinh dưỡng và tỷ lệ tử vong.- Kết luận: Tầm soát tiền sản các DTBSĐTH góp phần vào kết quả điều trị trẻ sơ sinh có phẫu thuật các bất thường bẩm sinh tiêu hóa. Abstract- Objectives: To discribe characteristics of prenatal diagnosis and treatment results in neonates with congenital digestive malformations (CDMs) operated at Children’s Hospital No 1.- Material and method: Descriptive cross - sectional study. Selection criteria: Neonates diagnosed with CDMs operated at Children’s Hospital No 1 from 01/2020 to 06/2021.- Results: 205 neonates with CDMs were operated. The percentage of pregnant women receiving prenatal examination, counsulting and diagnosis was 100% (HCM City) and 95.6% (provinces). The most common prenatal diagnostic tool was ultrasound (97.6%). 42.5% cases were found CDMs by prenatal ultrasound. 45.8% of neonates were not examined immediately after birth. There were 22.9% cases of treatment failure at the local hospitals and then referral. The average age of neonates at admission was 5.19 days old. The average hospital stay was 25.4 days. 48.8% recorded complications. 77.1% of neonates were discharged safely. The mortality rate was 8.3%. There was a statistically significant difference in the rate of examination immediately after birth, the reason for referral, time of hospital transfer, multiple birth defects and chromosomal abnormalities, number of days of treatment, malnutrition rate, and mortality rate when comparing between the group of children whose mothers were diagnosed with prenatal ultrasound and the remaining group of neonates.- Conclusions: Prenatal diagnosis of CDMs contributes to the treatment outcome of neonates with congenital gastrointestinal abnormalities. DOI: 10.59715/pntjmp.1.3.17

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