Nhận xét kết quả sớm của tiêm Botulinum toxin A trong điều trị bàng quang tăng hoạt tại Bệnh viện Bình Dân

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Tác giả: Vũ Phương Đỗ, Phúc Cẩm Hoàng Nguyễn, Hữu Đoàn Phạm, Ngọc Thảo Linh Trần

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y Dược học Phạm Ngọc Thạch, 2023

Mô tả vật lý: tr.108

Bộ sưu tập: Metadata

ID: 339384

Thêm vào giỏ Liên kết toàn văn

- Giới thiệu: Bàng quang tăng hoạt là một rối loạn đường tiểu dưới thường gặp. Người mắc bàng quang tăng hoạt đều dễ bị ảnh hưởng sức khỏe thể chất và tinh thần nghiêm trọng. Bên cạnh thay đổi lối sống, điều trị bảo tồn thì tiêm Botulinum toxin A vào cơ bàng quang cũng được ứng dụng rộng rãi trong việc điều trị bàng quang tăng hoạt.- Phương pháp nghiên cứu: Đây là nghiên cứu báo cáo loạt trường hợp, nhằm đánh giá sự cải thiện về triệu chứng ở bệnh nhân bàng quang tăng hoạt sau khi tiêm Botulinum toxin A vào cơ bàng quang. Chúng tôi tiến hành nghiên cứu trên 16 bệnh nhân được chẩn đoán bàng quang tăng hoạt và điều trị bằng tiêm bàng quang Botulinum toxin A tại khoa Niệu Nữ - Niệu Chức Năng, bệnh viện Bình Dân. Điểm về triệu chứng và điểm chất lượng cuộc sống được ghi nhận dựa vào bảng điểm triệu chứng OABSS (Overactive Bladder Symptom Score) và bảng câu hỏi rút gọn OAB-q SF (Overactive Bladder Questionnaire Short Form) để so sánh trước và sau can thiệp.- Kết quả: Tuổi trung bình của bệnh nhân là 43,1 ± 16,4, trong đó có 15 bệnh nhân nữ (93,75%) và 1 bệnh nhân nam (6,25%). Tất cả các giá trị điểm câu hỏi sau can thiệp 4 tuần đều có sự cải thiện có ý nghĩa thống kê so với trước mổ (p <
0,05).- Kết luận: Việc tiêm Botulinum toxin A trong điều trị bàng quang tăng hoạt khá an toàn và hiệu quả trong cải thiện chất lượng cuộc sống những bệnh nhân đã kháng trị cholinergic. Abstract- Introduction: Overactive bladder is a common lower urinary tract disorder. Patients with overactive bladder are susceptible to severe physical and mental health effects. Besides lifestyle changes and conservative treatment, Botulinum toxin A injection into the bladder muscle is widely used to treat overactive bladder.- Methods: This is a case series report study. We surveyed 16 patients diagnosed with overactive bladder and treated with Botulinum toxin A bladder injection at the Department of Urology - Functional Urology, Binh Dan Hospital. Symptom score and quality of life were recorded based on OABSS (Overactive Bladder Symptom Score) and OAB-q SF (Overactive Bladder Questionnaire Short Form) to compare before and after the intervention.- Results: The mean age of the patients was 43,1 ± 16,4, in which there were 15 female patients (93,75%) and 1 male patient (6,25%). After four weeks of intervention, all question scores had a statistically significant improvement compared to before intervention (p <
0,05).- Discussion: The OABSS and OAB-q SF questionnaire results in the study showed positive results. After four weeks of intervention, the patient’s quality of life has markedly improved. This preliminary studies show that Botulinum toxin A is a good treatment choice in patients with overactive bladder who are resistant to anticholinergic drugs. During the follow - up period, no severe complications were detected after the intervention.- Conclusion: Botulinum toxin A injection in the treatment of overactive bladder is relatively safe and effective in improving the quality of life of patients who are already resistant to anticholinergic therapy. DOI: 10.59715/pntjmp.1.4.12

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