ĐẶC ĐIỂM LÂM SÀNG, NỘI SOI VÀ MÔ BỆNH HỌC CỦA BỆNH NHÂN UNG THƯ BIỂU MÔ TUYẾN HANG VỊ DẠ DÀY

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Tác giả: Hồng Thái Dương, Phú Hùng Nguyễn, Ngọc Thụy Trần

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Khoa học và Công nghệ - Đại học Thái Nguyên, 2023

Mô tả vật lý: tr.18-23

Bộ sưu tập: Metadata

ID: 339623

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Nghiên cứu mô tả một số triệu chứng lâm sàng thường gặp, hình ảnh đại thể của ung thư thông qua nội soi và đặc điểm mô bệnh học của ung thư biểu mô tuyến hang vị dạ dày. Đối tượng nghiên cứu gồm 150 trường hợp ung thư biểu mô tuyến dạ dày được phẫu thuật tại bệnh viện K Hà Nội bằng phương pháp nghiên cứu mô tả cắt ngang. Kết quả cho thấy tỷ lệ ung thư dạ dày cao nhất ở nhóm tuổi 60-69, tỷ lệ nam/nữ là: 1,94/1. Các triệu chứng toàn thân và cơ năng thường gặp đau vùng thượng vị (99,3%). Tổn thương có hình ảnh dạng loét chiếm 53,3%, tiếp theo là dạng nấm chiếm 36%, dạng polyp là 2,7% và dạng thâm nhiễm là 8%. Theo phân loại Lauren, thể ruột chiếm 72,7%, thể lan tỏa chiếm 22,7%, thể hỗn hợp chiếm 4,7%. Theo hệ thống phân loại của WHO, có 58,7% các trường hợp là thể ống nhỏ, 22,7% thể tế bào nhẫn, 12% thể nhầy và 4,7% thể hỗn hợp và thể nhú là 2%. Về độ biệt hóa, có 19,3% thể biệt hóa tốt, 37,3% thể biệt hóa vừa và 43,3% thể biệt hóa kém. Hầu hết các bệnh nhân (98,7%) được phát hiện và phẫu thuật đã ở giai đoạn tiến triển (giai đoạn II đến giai đoạn IV).This study describes some clinical features, macroscopic images and histopathological characteristics of gastric adenocarcinoma tumors. The study subjects included 150 cases of gastric adenocarcinoma operated at Hanoi K hospital using a cross-sectional descriptive study method. The results revealed that the rate of stomach cancer is highest in the age group 60-69, male/female ratio: 1.94/1. The most common systemic and functional symptoms were epigastric pain (99.3%). Ulcerative lession was 53.3%, followed by polypoid (36%), polyps (2.7%), and infiltrates (8%). According to Lauren classification, intestinal type accounted for 72.7%, diffuse type was 22.7% and mixed type was 4.7%. According to WHO, 58.7% of cases are tubular adenocarcinoma, signet ring cell carcinoma was 22.7%, mucinous adenocarcinoma was 12%, mixed carcinoma was 4.7% and papillary adenocarcinoma was 2%. In terms of differentiation, 19.3% of cases was well differentiated, moderately differentiated was 37.3%, and poorly differentiated was 43.3%. All most patients (98.7%) were diagnosed and undergoing surgery at an advanced stage (stage II to stage IV).

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