Phân tích tình hình sử dụng thuốc điều trị viêm dạ dày mạn nhiễm Helicobacter pylori tại Bệnh viện Đa khoa thành phố Cần Thơ

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Tác giả: Thị Thanh Loan Đinh, Thị Thu Hồng Giang, Chí Toàn Nguyễn, Thị Thu Hương Nguyễn, Thị Kim Tươi Thái

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Nghiên cứu khoa học và Phát triển kinh tế, 2023

Mô tả vật lý: tr.222

Bộ sưu tập: Metadata

ID: 341180

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Helicobacter pylori (H. pylori) chronic gastritis can lead to gastric cancer. Treatment guidelines for H. pylori have been updated based on the antimicrobial resistance of H. pylori. The study was conducted to analyze the situation of drug use to treat Helicobacter pyloriinduced chronic gastritis in outpatients, and evaluate the therapeutic outcome as well as medication adherence in investigation samples at Can Tho City General Hospital in 2020. A cross-sectional descriptive study analyzed 166 outpatients’medical records, and the 8-item Morisky Medication Adherence Scale was applied to investigate medical adherence. The results showed that the first-line H. pylori treatment regimen was used in which the first combination of 3 drugs PPI + Amoxicillin + Clarithromycin was the highest applied prescription (76,51%). The most used PPI drug was Esomeprazol, accounting for 66,27%. The ratio of H. pylori eradication after treatment was 88,55%. The level of good medical adherence was recorded at 66,27%. The rate of patients without clinical symptoms of the disease was 33,53%. Our results indicated a relationship between the degree of treatment adherence and the ratio of H. pylori eradication. Treatment guidelines need to be continuously updated, and health education and counseling improved.Viêm dạ dày mạn nhiễm Helicobacter pylori (H. pylori) có thể dẫn đến ung thư dạ dày. Các phác đồ điều trị viêm dạ dày mạn nhiễm H. pylori được cập nhật với tình hình đề kháng kháng sinh của vi khuẩn. Nghiên cứu được thực hiện nhằm phân tích tình hình sử dụng thuốc điều trị viêm dạ dày mạn nhiễm H. pylori ở bệnh nhân ngoại trú và đánh giá hiệu quả điều trị cũng như sự tuân thủ điều trị của bệnh nhân tại Bệnh viện Đa khoa thành phố Cần Thơ năm 2020. Nghiên cứu mô tả cắt ngang dựa trên hồi cứu thông tin thu thập từ 166 bệnh án ngoại trú và dùng thang đánh giá tuân thủ Morisky – 8 để đánh giá tuân thủ điều trị. Kết quả nghiên cứu cho thấy phác đồ điều trị H. pylori bậc 1 được sử dụng cho tất cả bệnh nhân trong đó liệu pháp đầu tiên kết hợp 3 loại thuốc ức chế bơm proton (PPI) + Amoxicillin + Clarithromycin được sử dụng nhiều nhất (76,51%). Thuốc PPI được sử dụng nhiều nhất là Esomeprazol chiếm 66,27%. Tỷ lệ diệt trừ H. pylori sau điều trị đạt 88,55%. Mức độ tuân thủ điều trị tốt của nhóm bệnh nhân nghiên cứu là 66,27%. Tỷ lệ bệnh nhân không còn các triệu chứng lâm sàng của bệnh là 33,53%. Có mối liên hệ giữa mức độ tuân thủ và tỷ lệ diệt trừ H. pylori. Cần cập nhật liên tục các hướng dẫn điều trị, cải thiện khâu tư vấn và giáo dục sức khỏe.

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