SODIUM SULFIDE-PROMOTED REACTION OF 2-AMINOBENZAMIDE AND BENZYL ALCOHOLS WITH ELEMENTAL SULFUR: A NOVEL APPROACH WITH 2-ARYL-QUINAZOLIN-4(3H)

• Tác giả: Thi Yen Oanh Doan, Quoc Anh Ngo, Ngoc Binh Vo
• Ngôn ngữ: eng
• Thông tin xuất bản: Tạp chí Khoa học - Trường Đại học Sư phạm Hà Nội: Khoa học Tự nhiên, 2023
• Mô tả vật lý: tr.83
• Bộ sưu tập: Metadata
• ID: 341530

Tóm tắt

A simple metal- and solvent-free method for the synthesis of 2-aryl- 4(3H)-quinazolinone derivatives from 2-aminobenzamide and benzyl alcohols in the presence of S8\DMSO as an oxidizing agent and promoted by Na2S.5H2O has been reported. Five 2-aryl-4(3H)-quinazolinone derivatives were synthesized with yields from 23% to 86%.