Tỷ lệ đạt mục tiêu LDL - C ở người cao tuổi có hội chứng vành mạn tại Phòng khám Tim mạch Bệnh viện Thống Nhất theo Hội Tim mạch Châu Âu / Hội Xơ vữa Động mạch Châu Âu 2019

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Tác giả: Phạm Trọng Khang Hà, Sĩ Dũng Hồ, Đức Công Nguyễn, Văn Bé Hai Nguyễn

Ngôn ngữ: vie

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Thông tin xuất bản: Tạp chí Y Dược học Phạm Ngọc Thạch, 2024

Mô tả vật lý: tr.117

Bộ sưu tập: Metadata

ID: 341836

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Đặt vấn đề: Kiểm soát low - density lipoprotein cholesterol (LDL - C) tối ưu là một trong những mục tiêu chính trong phòng ngừa biến cố tim mạch thứ phát trên người cao tuổi có hội chứng vành mạn (HCVM). Mục tiêu: Tìm hiểu tỷ lệ kiểm soát LDL - C ở người cao tuổi có HCVM tại phòng khám Tim mạch bệnh viện Thống Nhất từ tháng 11/2021 đến tháng 05/2022 theo khuyến cáo của Hội Tim mạch Châu Âu (ESC) và Hội Xơ vữa Động mạch Châu Âu (EAS) 2019. Phương pháp nghiên cứu: Nghiên cứu cắt ngang mô tả, thu thập thông tin trên 143 bệnh nhân cao tuổi về tuổi, giới và xét nghiệm bộ lipid máu để đánh giá tình trạng kiểm soát LDL - C. Kết quả: Trong 143 người cao tuổi có HCVM được khảo sát, có 94 nam (65,7%) và 49 nữ (34,3%). Tuổi trung bình là 73,84 ± 8,52, trong đó nhóm tuổi sơ lão chiếm 40,6%, trung lão chiếm 31,4%, và đại lão chiếm 28,0%. Tỷ lệ đạt mục tiêu LDL - C (<
1,4 mmol/L) chung theo khuyến cáo của ESC/EAS năm 2019 là 15,4%. LDL - C trung bình chung là 2,14 ± 1,09 mmol/L, trong đó, giá trị LDL - C của nhóm đạt mục tiêu là 1,01 ± 0,27 mmol/L, của nhóm không đạt mục tiêu là 2,34 ± 1,05 mmol/L, với p <
0,001. Ở nhóm đạt mục tiêu, tỷ lệ nam giới là 72,7%, nữ giới là 27,3%, với p = 0,45. Theo nhóm tuổi, tỷ lệ các nhóm sơ lão, trung lão, đại lão đạt mục tiêu điều trị lần lượt là 50,0%, 31,8%, 18,2%, với p = 0,48. Kết luận: Tỷ lệ đạt mục tiêu LDL - C của bệnh nhân cao tuổi có HCVM tại phòng khám Tim mạch bệnh viện Thống Nhất theo khuyến cáo của ESC/EAS năm 2019 là chưa cao. Tỷ lệ đạt mục tiêu LDL - C không liên quan đến giới tính và phân nhóm tuổi.Abstract Background: Optimal control of low - density lipoprotein cholesterol (LDL - C) is one of the main goals in the prevention of secondary cardiovascular events in the elderly with chronic coronary syndromes (CCS). Objectives: To investigate the rate of LDL - C control in older people with CCS at Cardiology clinic in Thong Nhat Hospital from November 2021 to May 2022 as recommended by the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS) 2019. Methods: A descriptive cross - sectional study, collecting information from 143 elderly patients about age, sex, and blood lipid test to assess the rate of LDL - C goal achievement. Results: Among 143 elderly people with CCS who were surveyed, there were 94 men (65.7%) and 49 women (34.3%). The mean age was 73.84 ± 8.52, in which the young - old group accounted for 40.6%, the middle - old 31.4%, and the old - old group accounted for 28.0%. The ESC/EAS recommended total LDL - C goal achievement rate for 2019 was 15.4% (<
1,4 mmol/L). The average LDL - C level was 2.14 ± 1.09 mmol/L, in which, the LDL - C value of the goal achievement group was 1.01 ± 0.27 mmol/L, of the goal non - achievement group was 2.34 ± 1.05 mmol/L, with p <
0.001. In the group that reached the target, the proportion of men was 72.7% and women were 27.3%, with p = 0.45. By age group, the percentages of the young - old, middle - old and old - old attaining the treatment goal were 50.0%, 31.8%, and 18.2%, respectively, with p = 0.48. Conclusions: The rate of achieving the overall LDL - C goal of older patients with CCS at Cardiology clinic in Thong Nhat Hospital as recommended by ESC/EAS in 2019 is not high enough. LDL - C goal attainment rate was not related to sex and age subgroups. DOI: 10.59715/pntjmp.2.3.14

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