Science, technology and innovation (STI) are generally accepted as major drivers of growth and can help address poverty and directly improve the well-being of different groups in society. However, under certain circumstances, STI can reinforce social exclusion and inequalities. This book explores discourses around directionality and the importance of Innovation for Inclusive Development (IID) in addressing policy questions that explore the relationship between IID with inequalities in income and opportunities. It seeks to unpack the concept of IID and what it means in a country such as South Africa - a country characterised by endemic poverty, deepening inequality, and high levels of unemployment. The book is largely original and based on a critique of existing literature to expose specific issues or bolster specific arguments about the role of IID in equitable and inclusive development. This book has been written by various scholars who understand the various notions of IID and how it can possibly be applied and the relevance of such knowledge for policy, programmes and practice.