Nano copper (CuNPs) has recently emerged as a promising material with potential applications in agriculture and biotechnology. This paper aims to review the current state of knowledge regarding the potential of nano Cu in these fields. We begin by summarizing the synthesis methods and properties of nano Cu, including its unique physical and chemical properties that make it an attractive candidate for use in agriculture and biotechnology. We then discuss the potential applications of nano Cu in plant growth promotion, disease control, and environmental remediation. In addition, we review the current understanding of the mechanisms underlying the effects of nano Cu on plant growth and disease resistance. Finally, we discuss the challenges and opportunities associated with the use of nano Cu in these fields, including potential risks to human health and the environment. Overall, this paper highlights the potential of nano Cu as a versatile and effective tool for improving agricultural productivity and environmental sustainability.